La selección del tipo de espéculo que se vaya a utilizar dependerá de los datos obtenidos en el interrogatorio a la paciente, así como de la edad y paridad. Antecedentes Patológicos 9. Antecedentes Familiares Interrogatorio por Aparatos y Sistemas Historia Pediátrica Historia y Examen Ginecológico [30] [31][32] Métodos Previo interrogatorio ginecológico, se realizó citología exfoliativa cervico- vaginal (papanicolaou) a todas las pa- cientes que acudieron al.

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VIN is a heterogeneous pathological entity with a usual type warty, basaloid and mixed and a differentiated type. The incidence of the disease is increasing, especially in young women. The high-risk human papilomavirus HR-HPV infection, human immunodeficiency virus HIV infection, smoking, cervical, vaginal and rectal intraepithelial neoplasia are considered to be high risk factors for ginexologico of VIN.

There are no specific symptoms or vulvar ginecolpgico aspects of VIN. However, a clinical lesion is always present.

Técnica de colocación del espéculo.

Liberal vulvar biopsies under colposcopy guidance should be done. Patients with diagnosis of VIN harbor an increased risk for vulvar invasive cancer. Surgical excision and laser CO 2 vaporization are the most popular therapeutic modalities for VIN treatment, both with high rates of recurrence. A close follow-up of the patients is advised. Topical imiquimod seems to be a promising treatment option.

Mais recentemente, Joura et al. EmBuscema et al. Int J Gynecol Pathol. Inter-observer variation in histopathological diagnosis and grading of vulvar intraepithelial neoplasia: Squamous vulvar intraepithelial neoplasia: Vulvar intraepithelial neoplasia III: Analysis of clonality and Interrogatoeio infection in benign, hyperplastic, premalignant, and malignant lesions of the vulvar mucosa. Am J Clin Pathol.


Presence and type of oncogenic papillomavirus in classic and in differentiated vulvar intraepithelial neoplasia and keratinizing vulvar squamous cell carcinoma. Am J Surg Pathol. Eur J Gynaecol Oncol. Analysis of alterations adjacent to invasive vulvar carcinoma and their relationship with associated carcinoma: Mene A, Buckley CH.

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Involvement of the vulval skin appendages by intraepithelial neoplasia. Br J Obstet Gynaecol. Epidermal thickness and skin appendage involvement in vulvar intraepithelial neoplasia.

In situ and invasive vulvar cancer incidence trends to Am J Obstet Gynecol. Trends in vulvar neoplasia. Increasing incidence of vulvar intraepithelial neoplasia and squamous cell carcinoma of the vulva in young women. High-grade vulval intraepithelial neoplasia VIN 3: Genital warts, other sexually transmitted diseases, and vulvar cancer. Case-control study of cancer of the vulva. Cofactors with human papillomavirus in a population-based study of vulvar cancer.

J Natl Cancer Inst. Human papillomavirus type 16 and risk of preinvasive and invasive vulvar cancer: Effect of antiretroviral therapy on the incidence of genital warts and vulvar neoplasia among women with the human immunodeficiency virus. Vulvar, vaginal, and perianal intraepithelial neoplasia in women with or at risk for human immunodeficiency virus. Effect of cigarette smoking on cervical epithelial immunity: Histopathologic study of thin vulvar squamous cell carcinomas and associated cutaneous lesions: Husseinzadeh N, Recinto C.

Frequency of invasive cancer in surgically excised vulvar lesions with intraepithelial neoplasia VIN 3. Cyclooxigenase 2 expression in cervical intraepithelial neoplasia and vulvar cancer.

J Low Genit Tract Dis. P53 expression in vulvar carcinoma, vulvar intraepithelial neoplasia, squamous cell hyperplasia and lichen sclerosus. Int J Gynecol Cancer. Vulvar carcinoma in situ. The relevance of various vulvar epithelial changes in the early detection of squamous cell carcinoma of the vulva.


Cytological evaluation correlates poorly with histological diagnosis of vulvar neoplasias.

Arch Pathol Lab Med. Vulvoscopy in benign and premalignant vulvar lesions: Clinical stains for cancer. Intraepithelial carcinoma of the vulva.

Carcinoma in situ of the vulva. Rutledge F, Sinclair M.

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Treatment of intraepithelial carcinoma of the vulva interrovatorio skin excision and graft. Skinning vulvectomy for the treatment of multifocal vulvar intraepithelial neoplasia.

Surgical approach to multifocal carcinoma in situ of the vulva. Wide local excision in the treatment of vulvar carcinoma in-situ: Evaluation of different treatment modalities for giencologico intraepithelial neoplasia VIN: CO 2 laser vaporization, photodynamic therapy, excision and vulvectomy.

Laser ablation of surgical margins after excisional partial vulvectomy for VIN: Treatment of vulvar intraepithelial neoplasia with topical imiquimod. N Engl J Med. Efficacy ginecologicco a quadrivalent prophylactic human papillomavirus types 6, 11, 16, 18 L1 virus-like-particle vaccine against high-grade vulval and vaginal lesions: All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.

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