Request PDF on ResearchGate | On Nov 1, , H. Benamer and others published Angor instable. Introduction. Request PDF on ResearchGate | On Dec 1, , F. Haddad and others published Angor instable révélant une coronarite et une aortite chez un patient ayant. Preferred Name. ANGINE DE POITRINE. Synonyms. ANGOR INSTABLE. INSUFFISANCE CORONAIRE. CRISE ANGINEUSE. ANGINE D’EFFORT. DOULEUR.
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The major risk of atherosclerotic disease is the occurrence of an acute coronary syndrome. The pathogenesis of instable angina involves the formation of an arterial thrombus as a consequence insttable the rupture of an atheromatous plaque. This risk of plaque rupture appears to depend on plaque morphology rather than plaque size or severity of stenosis.
Ratio of lipid core to fibrous determined by the balance between smooth muscle cells proliferation and extracellular matrix synthesis stabilizing the plaque and macrophages which degrade collagen, determine the plaque vulnerability. The fibrous cap weakness leads to the plaque activation, plaque fissure or erosion activating a thrombotic cascade.
A general inflammation or prothrombotic states are probably involved suggesting the need for a systemic therapeutic in addition with the treatment of the culprit lesion. Previous Article Angor instable.
Annales de Biologie Clinique
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Unstable angina | English to French | Medical: Cardiology
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